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Lurie Children’s Hospital, Stanley Manne Research Institute, and Northwestern Memorial Hospital. We also acknowledge the in-kind study support from the Ann & Robert H.
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This publication was supported by the National Institute on Aging of the National Institutes of Health under award number R43AG067835. acknowledges additional support from startup funding from the University of Hawaiʻi, as a junior investigator from the National Institute of General Medical Sciences of the National Institutes of Health (P20GM113134) and the Hawaiʻi Community Foundation (Robert C. Funding: We would like to acknowledge funding support provided by the Querrey Simpson Institute for Bioelectronics at Northwestern University. Rugg in assisting with study administration as well as T. A portion of this work was also performed in the University of California, Santa Barbara Nanofabrication Facility. This work used Northwestern University Micro/Nano Fabrication Facility (NUFAB) and the Pritzker Nanofabrication Facility, part of the Pritzker School of Molecular Engineering at the University of Chicago, which are both partially supported by Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF ECCS-1542205), a node of the National Science Foundation’s National Nanotechnology Coordinated Infrastructure. The wearable microfluidic technologies and smartphone-based analytics reported here establish the foundation for diagnosis of CF outside of clinical settings. Clinical validation studies involving patients with CF and healthy subjects, across a spectrum of age groups, support clinical equivalence compared to existing device platforms in terms of accuracy and demonstrate meaningful reductions in rates of leakage. Real-time image analysis of chloride reagents allows for quantitative assessment of chloride concentrations using a smartphone camera, without requiring extraction of sweat or external analysis.
#R STUDIO STICKERS SKIN#
Intimate, conformal coupling with the skin supports nearly perfect efficiency in sweat collection without leakage. Here, we introduce a soft, epidermal microfluidic device (“sweat sticker”) designed for the simple and rapid collection and analysis of sweat. The collection and analysis of sweat using conventional wrist-strapped devices and iontophoresis can be cumbersome, particularly for infants with fragile skin, who often have insufficient sweat production.
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Early diagnosis via quantitative assessment of sweat chloride allows prompt initiation of care and is critically important to extend life expectancy and improve quality of life. The concentration of chloride in sweat remains the most robust biomarker for confirmatory diagnosis of cystic fibrosis (CF), a common life-shortening genetic disorder. Reeder, Aurélie Hourlier-Fargette, Amay J. Jeang, Joseph Chafetz, … Show All …, Hannah Gaertner, Grace Young, Steve Rebollo, Jeffrey B. Curtis, Daniel Franklin, Kerem Guventurk, William J. Plus, every Society6 purchase pays an artist-empowering creativity around the world.Tyler R. You can even take your aesthetic to your wardrobe with our array of apparel and bags. Find all the trending home decor styles like rustic, modern, patterns and more so you can make every room in your home from the bathroom to the bedroom to the kitchen feel uniquely you. Need more proof? We've got everything from minimalist wall art to beautiful original photography. Whether you're looking for art prints, tapestries, throw pillows, comforters, shower curtains, T Shirts or iPhone cases-we've truly got something for everyone. Everything is made to order-and with so many styles to choose from, Society6 makes it easy to match your exact taste. Choose your favorite and pair it with our best-in-class selection of wall art, home decor, bed and bath, apparel, tech accessories, furniture and lifestyle goods for your everyday. Society6 is home to a thriving community of independent artists worldwide, each with their own unique designs.